diff --git a/core/tx_pool.go b/core/tx_pool.go
index 563dcf5d57..b0e43fd468 100644
--- a/core/tx_pool.go
+++ b/core/tx_pool.go
@@ -192,6 +192,26 @@ func (config *TxPoolConfig) sanitize() TxPoolConfig {
 		log.Warn("Sanitizing invalid txpool price bump", "provided", conf.PriceBump, "updated", DefaultTxPoolConfig.PriceBump)
 		conf.PriceBump = DefaultTxPoolConfig.PriceBump
 	}
+	if conf.AccountSlots < 1 {
+		log.Warn("Sanitizing invalid txpool account slots", "provided", conf.AccountSlots, "updated", DefaultTxPoolConfig.AccountSlots)
+		conf.AccountSlots = DefaultTxPoolConfig.AccountSlots
+	}
+	if conf.GlobalSlots < 1 {
+		log.Warn("Sanitizing invalid txpool global slots", "provided", conf.GlobalSlots, "updated", DefaultTxPoolConfig.GlobalSlots)
+		conf.GlobalSlots = DefaultTxPoolConfig.GlobalSlots
+	}
+	if conf.AccountQueue < 1 {
+		log.Warn("Sanitizing invalid txpool account queue", "provided", conf.AccountQueue, "updated", DefaultTxPoolConfig.AccountQueue)
+		conf.AccountQueue = DefaultTxPoolConfig.AccountQueue
+	}
+	if conf.GlobalQueue < 1 {
+		log.Warn("Sanitizing invalid txpool global queue", "provided", conf.GlobalQueue, "updated", DefaultTxPoolConfig.GlobalQueue)
+		conf.GlobalQueue = DefaultTxPoolConfig.GlobalQueue
+	}
+	if conf.Lifetime < 1 {
+		log.Warn("Sanitizing invalid txpool lifetime", "provided", conf.Lifetime, "updated", DefaultTxPoolConfig.Lifetime)
+		conf.Lifetime = DefaultTxPoolConfig.Lifetime
+	}
 	return conf
 }
 
diff --git a/core/tx_pool_test.go b/core/tx_pool_test.go
index 28b1c7c83a..f4f7758a6e 100644
--- a/core/tx_pool_test.go
+++ b/core/tx_pool_test.go
@@ -1129,9 +1129,8 @@ func TestTransactionPendingMinimumAllowance(t *testing.T) {
 	blockchain := &testBlockChain{statedb, 1000000, new(event.Feed)}
 
 	config := testTxPoolConfig
-	config.AccountSlots = 10
-	config.GlobalSlots = 0
 	config.AccountSlots = 5
+	config.GlobalSlots = 1
 	pool := NewTxPool(config, params.TestChainConfig, blockchain)
 	defer pool.Stop()
 
@@ -1473,6 +1472,7 @@ func TestTransactionPoolStableUnderpricing(t *testing.T) {
 	config := testTxPoolConfig
 	config.GlobalSlots = common.LimitThresholdNonceInQueue
 	config.GlobalQueue = 0
+	config.AccountSlots = config.GlobalSlots - 1
 
 	pool := NewTxPool(config, params.TestChainConfig, blockchain)
 	defer pool.Stop()